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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APBB1
All Species:
16.06
Human Site:
S174
Identified Species:
39.26
UniProt:
O00213
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00213
NP_001155.1
710
77244
S174
E
E
E
E
E
D
L
S
S
P
P
G
L
P
E
Chimpanzee
Pan troglodytes
XP_521814
848
91186
S307
E
E
E
E
E
D
L
S
S
P
P
G
L
P
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534037
724
78741
Q189
S
S
W
A
T
L
S
Q
G
S
P
S
Y
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXJ1
710
77450
S174
E
E
E
E
E
D
L
S
S
P
P
G
L
P
E
Rat
Rattus norvegicus
P46933
711
77638
S175
D
E
E
E
E
D
L
S
S
P
Q
G
L
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507097
616
68316
L111
E
L
R
G
R
G
V
L
R
H
L
F
L
P
F
Chicken
Gallus gallus
XP_420735
740
81441
S155
E
P
I
P
Q
D
S
S
S
C
E
I
L
P
S
Frog
Xenopus laevis
NP_001087003
610
66956
D105
P
A
K
S
E
L
T
D
P
F
T
T
E
T
S
Zebra Danio
Brachydanio rerio
XP_693392
869
95380
S340
A
S
P
R
K
P
Q
S
P
E
D
T
P
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787988
848
93773
E165
A
D
L
M
S
P
D
E
V
I
A
T
K
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
N.A.
78.3
N.A.
94.6
93.8
N.A.
38.8
45
51.5
39.5
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
83.7
N.A.
80.6
N.A.
97.1
96
N.A.
53.6
60.9
62.2
53.5
N.A.
N.A.
N.A.
N.A.
47.1
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
86.6
N.A.
20
40
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
6.6
N.A.
100
93.3
N.A.
26.6
46.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
0
10
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
50
10
10
0
0
10
0
0
0
0
% D
% Glu:
50
40
40
40
50
0
0
10
0
10
10
0
10
0
40
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
10
% F
% Gly:
0
0
0
10
0
10
0
0
10
0
0
40
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
10
0
10
0
0
0
% I
% Lys:
0
0
10
0
10
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
10
10
0
0
20
40
10
0
0
10
0
60
20
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
10
10
0
20
0
0
20
40
40
0
10
60
0
% P
% Gln:
0
0
0
0
10
0
10
10
0
0
10
0
0
0
0
% Q
% Arg:
0
0
10
10
10
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
20
0
10
10
0
20
60
50
10
0
10
0
0
30
% S
% Thr:
0
0
0
0
10
0
10
0
0
0
10
30
0
10
0
% T
% Val:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _